Electroporation

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Electroporation, or electropermeabilization, is a microbiology technique in which an electrical field is applied to cells in order to increase the permeability of the cell membrane, allowing chemicals, drugs, or DNA to be introduced into the cell.

This is how the latest DNA vaccines will be administered. They will not use a viral vector. Developing immune response to the viral vector could be a real problem, especially when a booster is required.

https://en.wikipedia.org/wiki/Electroporation#Drug_and_gene_delivery

https://www.pharmaceutical-technology.com/news/italy-coronavirus-vaccine-candidate/
 

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